In this work, a new sensitive analytical method has been developed and evaluated for the determination of the most commonly\nused gaseous anesthetics, desflurane, sevoflurane, and this latter�s hepatic metabolite hexafluoroisopropanol (HFIP) in the urine. In\naddition, an evaluation of anesthetics exposition on the urine levels of a small population of surgical operators has been performed\nand results are briefly discussed.
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